山梗菜碱（洛贝林）

    Date Updated: 13/FEB/2006
    Version 1.2
    Regulation (EC) No 1907/2006
    ________________________________________________________________________
    1 - Product and Company Information
    ________________________________________________________________________
    Product Name        L-LOBELINE FREE BASE    
    Product Number        L7149    
    Company
    Century Ba-Shi Building 22A-B,
    200020 Shanghai
    Technical Phone #        86-21-61415566    
    Fax 86-21-61415567
    E-mail Address
    ________________________________________________________________________
    2 - Hazards Identification
    ________________________________________________________________________
    SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
    Toxic by inhalation, in contact with skin and if swallowed.
    ________________________________________________________________________
    3 - Composition/Information on Ingredients
    ________________________________________________________________________
    Product Name        CAS #        EC no        Annex I    
    Index Number
    L-LOBELINE FREE BASE        90-69-7        202-012-3 None    
    Formula        C22H27NO2    
    Molecular Weight 337,5000 AMU
    Synonyms        8,10-Diphenyllobelionol *    
    2-(6-(beta-Hydroxy-phenethyl)-1-methyl-2-piperidy
    l)acetophenone *
    2-(6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperid
    inyl)-1-phenylethanone * Inflatine * Lobelin *
    (-)-Lobeline * alpha-Lobeline * Lobnico
    ________________________________________________________________________
    4 - First Aid Measures
    ________________________________________________________________________
    AFTER INHALATION
    If inhaled, remove to fresh air. If breathing becomes difficult,
    call a physician.
    AFTER SKIN CONTACT
    In case of skin contact, flush with copious amounts of water for
    at least 15 minutes. Remove contaminated clothing and shoes.
    Call a physician.
    AFTER EYE CONTACT
    In case of contact with eyes, flush with copious amounts of
    water for at least 15 minutes. Assure adequate flushing by
    separating the eyelids with fingers. Call a physician.
    AFTER INGESTION
    If swallowed, wash out mouth with water provided person is
    conscious. Call a physician.
    ________________________________________________________________________
    5 - Fire Fighting Measures
    ________________________________________________________________________
    EXTINGUISHING MEDIA
    Suitable: Carbon dioxide, dry chemical powder, or appropriate
    foam.
    SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
    Wear self-contained breathing apparatus and protective clothing
    to prevent contact with skin and eyes.
    ________________________________________________________________________
    6 - Accidental Release Measures
    ________________________________________________________________________
    PROCEDURE(S) OF PERSONAL PRECAUTION(S)
    Wear respirator, chemical safety goggles, rubber boots, and
    heavy rubber gloves.
    METHODS FOR CLEANING UP
    Sweep up, place in a bag and hold for waste disposal. Avoid
    raising dust. Ventilate area and wash spill site after material
    pickup is complete.
    ________________________________________________________________________
    7 - Handling and Storage
    ________________________________________________________________________
    ________________________________________________________________________
    8 - Exposure Controls / Personal Protection
    ________________________________________________________________________
    ENGINEERING CONTROLS
    Mechanical exhaust.
    PERSONAL PROTECTIVE EQUIPMENT
    Respiratory Protection: Use respirators and components tested and
    approved under appropriate government standards such as NIOSH (US)
    or CEN (EU). Where risk assessment shows air-purifying respirators
    are appropriate use a full-face particle respirator type N99 (US)
    or type P2 (EN 143) respirator cartridges as a backup to
    engineering controls. If the respirator is the sole means of
    protection, use a full-face supplied air respirator.
    Hand Protection: Compatible chemical-resistant gloves.
    Eye Protection: Chemical safety goggles.
    ________________________________________________________________________
    9 - Physical and Chemical Properties
    ________________________________________________________________________
    Appearance        Physical State: Solid    
    Property        Value        At Temperature or Pressure    
    pH        N/A    
    BP/BP Range        N/A    
    MP/MP Range        N/A    
    Flash Point        N/A    
    Flammability        N/A    
    Autoignition Temp        N/A    
    Oxidizing Properties        N/A    
    Explosive Properties        N/A    
    Explosion Limits        N/A    
    Vapor Pressure        N/A    
    Partition Coefficient        N/A    
    Viscosity        N/A    
    Vapor Density        N/A    
    Saturated Vapor Conc. N/A
    Evaporation Rate        N/A    
    Bulk Density        N/A    
    Decomposition Temp.        N/A    
    Solvent Content        N/A    
    Water Content        N/A    
    Surface Tension        N/A    
    Conductivity        N/A    
    Miscellaneous Data        N/A    
    Solubility        N/A    
    ________________________________________________________________________
    10 - Stability and Reactivity
    ________________________________________________________________________
    STABILITY
    Stable: Stable.
    HAZARDOUS DECOMPOSITION PRODUCTS
    Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
    Nitrogen oxides.
    HAZARDOUS POLYMERIZATION
    Hazardous Polymerization: Will not occur
    ________________________________________________________________________
    11 - Toxicological Information
    ________________________________________________________________________
    RTECS NUMBER: OJ8480000
    ACUTE TOXICITY
    LD50
    Intraperitoneal
    Mouse
    43500 UG/KG
    LD50
    Intravenous
    Mouse
    6300 UG/KG
    LD50
    Subcutaneous
    Rabbit
    35 MG/KG
    SIGNS AND SYMPTOMS OF EXPOSURE
    Stomach pains, vomiting, diarrhea. Exposure can cause:
    ROUTE OF EXPOSURE
    Multiple Routes: Harmful if swallowed, inhaled, or absorbed
    through skin. May cause irritation.
    TARGET ORGAN INFORMATION
    Central nervous system. Peripheral nervous system.
    ________________________________________________________________________
    12 - Ecological Information
    ________________________________________________________________________
    No data available.
    ________________________________________________________________________
    13 - Disposal Considerations
    ________________________________________________________________________
    SUBSTANCE DISPOSAL
    Dissolve or mix the material with a combustible solvent and burn
    in a chemical incinerator equipped with an afterburner and
    scrubber. Observe all federal, state, and local environmental
    regulations.
    ________________________________________________________________________
    14 - Transport Information
    ________________________________________________________________________
    RID/ADR
    UN#: 1544
    Class: 6.1
    PG: III
    Proper Shipping Name: Alkaloids, solid, n.o.s.
    IMDG
    UN#: 1544
    Class: 6.1
    PG: III
    Proper Shipping Name: Alkaloids, solid, n.o.s.
    Marine Pollutant: No
    Severe Marine Pollutant: No
    Technical Name: Required
    IATA
    UN#: 1544
    Class: 6.1
    PG: III
    Proper Shipping Name: Alkaloids, solid, n.o.s.
    Inhalation Packing Group I: No
    Technical Name: Required
    ________________________________________________________________________
    15 - Regulatory Information
    ________________________________________________________________________
    CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
    INDICATION OF DANGER: T
    Toxic.
    R-PHRASES: 23/24/25
    Toxic by inhalation, in contact with skin and if swallowed.
    S-PHRASES: 36/37/39-45
    Wear suitable protective clothing, gloves, and eye/face
    protection. In case of accident or if you feel unwell, seek
    medical advice immediately (show the label where possible).
    COUNTRY SPECIFIC INFORMATION
    Germany
    WGK: 3
    Self-Classification
    ________________________________________________________________________
    16 - Other Information
    ________________________________________________________________________
    WARRANTY
    The above information is believed to be correct but does not
    purport to be all inclusive and shall be used only as a guide. The
    information in this document is based on the present state of our
    knowledge and is applicable to the product with regard to
    appropriate safety precautions. It does not represent any
    shall not be held liable for any damage resulting from handling or
    from contact with the above product. See reverse side of invoice
    or packing slip for additional terms and conditions of sale.
    unlimitedpaper copies for internal use only.
    DISCLAIMER
    For R&D use only. Not for drug, household or other uses.

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模块 15 - 法规信息
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模块16 - 其他信息
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